Departamento de Ingeniería Química y Biotecnología

Laboratorio de Biología Molecular e Ingeniería Genética

 Laboratorio de Biología Molecular e Ingeniería Genética

Equipos e instrumentos

  • Termocicladores
  • Cámaras de electroforesis

Miembros permanentes

Académicos responsables

Proyectos asociados

  • PROYECTO FONDECYT 1121088: "Improvement of the Lignocellulose Hydrolysis by Use of Auxiliary Enzymes". M. O. Salazar, investigador responsable, M.E. Lienqueo, co investigador. 2012-2014.
  • FONDEF D08-I-1051: "Vectores adenovirales para la terapia génica en el tratamiento del alcoholismo", J. Asenjo, investigador responsable. Co-investigadores, B. Andrews y M.E Lienqueo. 2009- 2013.
  • CONICYT-AKA2008-2009: "Optimal treatment processes of lignocelluloses for bioethanol - consortium: Optbio". M.E. Lienqueo, investigador responsable.
  • 2012-2013: Deputy Director of the applied R+D project entitled "Production of a standardized and clinically tested food ingredient for the control of glycemia in diabetic and pre-diabetic patients" (11IDL2-10682), granted by the Development and Innovation Fund (FDI) of the Chilean Government Development Agency (CORFO).
  • FONDECYT 1130317: co-researcher in the project entitled "A systems biology approach for studying and understandingcellular processes involved in the regulation of intestinal iron absorption", granted by the ChileanNational Agency for Scientific and Technological Research (Fondecyt 1130317). 2013-2016
  • Royal Society Grant.2010 - 2012: "Biodiversity and Natural Products of Actinobacteria from hyper-arid desert soil", Investigador responsible, Juan Asenjo.
  • Conicyt VI-2010 065: 2010-2011"Support for international networking between Research Centers" Bioproducts Discovery & Development Centre (BDDC) University of Guelph-Biocomsa-U. de Chile.

Publicaciones

  • Flores, K. A., Salgado, J. C., Zapata-Torres, G., Gerdtzen, Z. P., Gonzalez, M. J., Hermoso, M. A., 2012, Effect of the electrostatic potential on the internalization mechanism of cell penetrating peptides derived from TIRAP. Biotechnology and Bioprocess Engineering 17:485-499. (ISI).
  • Gerdtzen, Z. P., 2012, Modeling Metabolic Networks for Mammalian Cell Systems: General Considerations, Modeling Strategies, and Available Tools, Advances in Biochemical Engineering/Biotechnology, Volume 127, 71-108. (ISI).
  • Jimenez, N. E., Wilkens, C. A. and Gerdtzen, Z. P., 2011, Engineering CHO cell metabolism for growth in galactose, BMC Proceedings 2011, 5 (Suppl 8):P119 doi:10.1186/1753-6561-5-S8-P119. (Pubmed).
  • Salinas A., Vega M., Lienqueo M.E., Garcia A., Carmona R., Salazar O. Cloning of novel cellulases from cellulolytic fungi: heterologous expression of a family 5 glycoside hydrolase from Trametesversicolor in Pichiapastoris. Enzyme and Microbial Technology (Submitted to Enzyme and Microbial Technology).
  • Salgado J. C., Olivera, A., Gerdtzen Z. P., Tapia V., Conca C., Núñez, M. T. (2011): "A kinetic model for the storage of iron in ferritin", Proceedings of the 2011 Annual Meeting of the American Institute of Chemical Engineers, 623z.
  • Olivera-Nappa, A., Andrews, B. A. and Asenjo, J. A. (2011): "Mutagenesis Objective Search and Selection Tool (MOSST): an algorithm to predict structure-function related mutations in proteins", BMC Bioinformatics 12(1): 122.
  • L. Parra, F. Reyes, J. P. Acevedo, O. Salazar, B. A. Andrews, J. A. Asenjo, (2008) Cloning and fusion expression of a cold-active lipase from marine Antarctic origin, Enzyme Microb Technol., 42 371-377.
  • Acevedo, J.P., Rodriguez, V., Saavedra, M., Muñoz, M., Salazar, O., Asenjo J.A. and Andrews, B.A. (2013) Cloning, expression and decoding of the cold adaptation of a new widely represented thermolabilesubtilisin-like protease, J. Applied Microbiol., 114, 352-363, DOI: 10.1111/jam.12033.
  • J. P. Acevedo, F. Reyes, L.P. Parra, O. Salazar, B.A. Andrews, J.A. Asenjo, (2008) Screening PCR mediated by CODEHOP and an improved genome walking method to obtain complete new genes of subtilisin-like serine proteases, J. Biotechnol.,.133, 277-286 .
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