Laboratorio de Cultivos de Células Animales

Equipos e instrumentos

• Fermentadores
• Estufas de cultivo
• Cámaras de flujo laminar

Académicos responsables

• Prof. Juan Asenjo
  Correo electrónico: juasenjo@ing.uchile.cl
• Prof. Barbara Andrews
  Correo electrónico: bandrews@ing.uchile.cl
• Prof. Ziomara Gerdtzen
  Teléfonos: +562 29784713 - +562 29784723

• Contacto
  Correo electrónico: asistenteicdb@ing.uchile.cl
  Dirección: Plaza Ercilla 847, Santiago, Chile

• Nancy Carrasco
  Jefe de laboratorio
  Teléfonos: +562 29784715 - +562 29784725

Proyectos asociados

• FONDEF D08-I-1051: 2009- 2013: "Vectores adenovirales para la terapia génica en el tratamiento del alcoholismo", J. Asenjo, Investigador responsable. Co-investigadores, B. Andrews y M. E Lienqueo.
• FONDECYT INICIACION 1190268: Optimization of antibody production in CHO cells through metabolic engineering and media design". Investigador responsable. 2009-2012.

Publicaciones

• Flores, K. A., Salgado, J. C., Zapata-Torres, G., Gerdtzen, Z. P., Gonzalez, M. J., Hermoso, M. A., 2012, Effect of the electrostatic potential on the internalization mechanism of cell penetrating peptides derived from TIRAP. Biotechnology and Bioprocess Engineering 17:485-499. (ISI).
• Gerdtzen, Z. P., 2012, Modeling Metabolic Networks for Mammalian Cell Systems: General Considerations, Modeling Strategies, and Available Tools, Advances in Biochemical Engineering/Biotechnology, Volume 127, 71-108. (ISI).
• Jimenez, N. E., Wilkens, C. A. and Gerdtzen, Z. P., 2011, Engineering CHO cell metabolism for growth in galactose, BMC Proceedings 2011, 5 (Suppl 8):P119 doi:10.1186/1753-6561-5-S8-P119. (Pubmed).
• Wilkens, C. A. and Gerdtzen, Z. P., 2011, Engineering CHO cells for improved central carbon and energy metabolism, BMC Proceedings 2011, 5 (Suppl 8):P120 doi:10.1186/1753-6561-5-S8-P120. (Pubmed).
• Baeza, D., Salgado, J. C. and Gerdtzen, Z. P., 2011, Design and simulation of a controller system for metabolic shift regulation in mammalian cells, BMC Proceedings 2011, 5(Suppl 8):P11 doi:10.1186/1753-6561-5-S8-P11. (Pubmed)-. Wilkens, C. A., Altamirano, C., Gerdtzen, Z. P., 2011, Comparative Metabolic Analysis of Lactate for CHO cells in Glucose and Galactose. Biotechnology and Bioprocess Engineering 16:714-724. (ISI).
• Martinez, V., Gerdtzen, Z. P., Andrews, B. A., and Asenjo, J. A., (2010) Viral vectors for the treatment of alcoholism: Use of metabolic flux analysis for cell cultivation and vector production, Metabolic Engineering, 12, 129-137.