Laboratorio de Cultivos de Células Animales

Equipos e instrumentos

Fermentadores
Estufas de cultivo
Cámaras de flujo laminar.

    Académicos responsables

    Prof. Juan Asenjo
    Mail: juasenjo@ing.uchile.cl

    Prof. Barbara Andrews
    Mail: bandrews@ing.uchile.cl

    Prof. Ziomara Gerdtzen
    Fonos: (56-2) 29784713 / (56-2) 29784723

    Contacto: asistenteicdb@ing.uchile.cl
    Dirección: Plaza Ercilla 847, Santiago, chile.
    Web: www.cibyb.uchile.cl
    Jefe de laboratorio: Nancy Carrasco.
    Fonos: (56-2) 29784715 / (56-2) 29784725

    Proyectos asociados

    -. FONDEF D08-I-1051: 2009- 2013: "Vectores adenovirales para la terapia génica en el tratamiento del alcoholismo", J. Asenjo, Investigador responsable. Co-investigadores, B. Andrews y M. E Lienqueo.

    -. FONDECYT INICIACION 1190268: Optimization of antibody production in CHO cells through metabolic engineering and media design". Investigador responsable. 2009-2012.

    Publicaciones

    -. Flores, K. A., Salgado, J. C., Zapata-Torres, G., Gerdtzen, Z. P., Gonzalez, M. J., Hermoso, M. A., 2012, Effect of the electrostatic potential on the internalization mechanism of cell penetrating peptides derived from TIRAP. Biotechnology and Bioprocess Engineering 17:485-499. (ISI)
    -. Gerdtzen, Z. P., 2012, Modeling Metabolic Networks for Mammalian Cell Systems: General Considerations, Modeling Strategies, and Available Tools, Advances in Biochemical Engineering/Biotechnology, Volume 127, 71-108. (ISI)
    -. Jimenez, N. E., Wilkens, C. A. and Gerdtzen, Z. P., 2011, Engineering CHO cell metabolism for growth in galactose, BMC Proceedings 2011, 5 (Suppl 8):P119 doi:10.1186/1753-6561-5-S8-P119. (Pubmed)
    -. Wilkens, C. A. and Gerdtzen, Z. P., 2011, Engineering CHO cells for improved central carbon and energy metabolism, BMC Proceedings 2011, 5 (Suppl 8):P120 doi:10.1186/1753-6561-5-S8-P120. (Pubmed)
    -. Baeza, D., Salgado, J. C. and Gerdtzen, Z. P., 2011, Design and simulation of a controller system for metabolic shift regulation in mammalian cells, BMC Proceedings 2011, 5(Suppl 8):P11 doi:10.1186/1753-6561-5-S8-P11. (Pubmed)-. Wilkens, C. A., Altamirano, C., Gerdtzen, Z. P., 2011, Comparative Metabolic Analysis of Lactate for CHO cells in Glucose and Galactose. Biotechnology and Bioprocess Engineering 16:714-724. (ISI)
    -. Martinez, V., Gerdtzen, Z. P., Andrews, B. A., and Asenjo, J. A., (2010) Viral vectors for the treatment of alcoholism: Use of metabolic flux analysis for cell cultivation and vector production, Metabolic Engineering, 12, 129-137.

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